PAK2 Antibody, KO Validated

• Background :

  The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

• NCBI Gene ID :

  5062

• Swiss Prot :

  Q13177

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PAK2 (NP_002568.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Validation :

  Antibody is Knockout validated.

• Field of Research :

  Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  HeLa

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 58kDa

• Fragment :

  IgG

• Symbol :

  PAK2

• NCBI Official Name :

  P21 protein (Cdc42/Rac) -activated kinase 2

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PAK2 Antibody: PAK65, PAKgammaGamma-PAK, PAK-2

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid