BUB1B Antibody

• Background:

  This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

• NCBI Gene ID:

  701

• Swiss Prot:

  O60566

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BUB1B (NP_001202.4) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  U-251MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 55kDa/120kDa

• Fragment:

  IgG

• Symbol:

  BUB1B

• Positive Control 2:

  HeLa

• Positive Control 3:

  Jurkat

• Positive Control 4:

  HT-29

• Positive Control 5:

  A-549

• Positive Control 6:

  COS-7

• NCBI Official Name:

  BUB1 mitotic checkpoint serine/threonine kinase B

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BUB1B, Bub1A, BUBR1, HBUBR1, Protein SSK1, SSK1, BUB1beta, MAD3L

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid