BUB1B Antibody

• Background :

  This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

• NCBI Gene ID :

  701

• Swiss Prot :

  O60566

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Monkey

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BUB1B (NP_001202.4) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cancer, Cell Cycle, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  U-251MG

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 55kDa/120kDa

• Fragment :

  IgG

• Symbol :

  BUB1B

• Positive Control 2 :

  HeLa

• Positive Control 3 :

  Jurkat

• Positive Control 4 :

  HT-29

• Positive Control 5 :

  A-549

• Positive Control 6 :

  COS-7

• NCBI Official Name :

  BUB1 mitotic checkpoint serine/threonine kinase B

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  BUB1B, Bub1A, BUBR1, HBUBR1, Protein SSK1, SSK1, BUB1beta, MAD3L

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid