MORC2 Antibody

• Background:

  This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

• NCBI Gene ID:

  22880

• Swiss Prot:

  Q9Y6X9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 60-250 of human MORC2 (NP_055756.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 118kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  MORC2

• Positive Control 2:

  293T

• Positive Control 3:

  Mouse thymus

• Positive Control 4:

  Mouse testis

• Positive Control 5:

  Rat testis

• NCBI Official Name:

  MORC family CW-type zinc finger 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CMT2Z, ZCW3, ZCWCC1, ATPase MORC2, zinc finger CW-type coiled-coil domain protein 1

• Tested Applications:

  WB

• Physical Properties:

  Liquid