PGA3 Antibody

• Background:

  This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.

• NCBI Gene ID:

  643834

• Swiss Prot:

  P0DJD8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 63-180 of human PGA3 (NP_001073275.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  C6

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 42kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PGA3

• Positive Control 2:

  U-251MG

• Positive Control 3:

  U-87MG

• Positive Control 4:

  SGC-7901

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Rat brain

• NCBI Official Name:

  Pepsin A-3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Pepsin A-3, Pepsinogen-3, PGA3

• Tested Applications:

  WB

• Physical Properties:

  Liquid