YAP1 Antibody

• Background :

  This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID :

  10413

• Swiss Prot :

  P46937

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human YAP1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle, Signal Transduction, Transcription

• Purification :

  Affinity purification

• Positive Control :

  DU145

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 75kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000IHC: 1:50 - 1:200

• Symbol :

  YAP1

• Positive Control 2 :

  HeLa

• Positive Control 3 :

  BT474

• Positive Control 4 :

  A-549

• Positive Control 5 :

  NIH/3T3

• Positive Control 6 :

  Mouse brain

• NCBI Official Name :

  Yes-associated protein 1

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  YAP1, YAP, YAP2, YAP65, YKI

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid