YAP1 Antibody

• Background:

  This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID:

  10413

• Swiss Prot:

  P46937

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human YAP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction, Transcription

• Purification:

  Affinity purification

• Positive Control:

  DU145

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 75kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000IHC: 1:50 - 1:200

• Symbol:

  YAP1

• Positive Control 2:

  HeLa

• Positive Control 3:

  BT474

• Positive Control 4:

  A-549

• Positive Control 5:

  NIH/3T3

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Yes-associated protein 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  YAP1, YAP, YAP2, YAP65, YKI

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid