P70 S6K Antibody

• Background:

  This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

• NCBI Gene ID:

  6198

• Swiss Prot:

  P23443

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 361-525 of human P70 S6K (NP_003152.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Immunology, Obesity, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Symbol:

  RPS6KB1

• Positive Control 2:

  293T

• Positive Control 3:

  Jurkat

• Positive Control 4:

  HepG2

• Positive Control 5:

  NIH/3T3

• Positive Control 6:

  Mouse lung

• NCBI Official Name:

  Ribosomal protein S6 kinase, 70kDa, polypeptide 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RPS6KB1, ribosomal protein S6 kinase, 70kD, polypeptide 1, PS6K, S6K, S6K1, STK14A, p70 (S6K) -alpha, p70-S6K, p70-alpha, p70 S6 kinase, alpha 1, alpha 2, serine/threonine kinase 14 alpha

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid