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D2HGDH Antibody

CAT: 0223-16-493Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-16-493Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
NCBI Gene ID
728294
Swiss Prot
Q8N465
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 322-521 of human D2HGDH (NP_689996.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 56kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
D2HGDH
Positive Control 2
Rat heart
NCBI Official Name
D-2-hydroxyglutarate dehydrogenase
NCBI Organism
Homo sapiens
Other Product Names
D2HGD, D-2-hydroxyglutarate dehydrogenase, mitochondrial
Tested Applications
WB
Physical Properties
Liquid

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