IL10RB Antibody

• Background:

  The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.

• NCBI Gene ID:

  3588

• Swiss Prot:

  Q08334

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human IL10RB (NP_000619.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 36kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  IL10RB

• Positive Control 2:

  293T

• Positive Control 3:

  Jurkat

• Positive Control 4:

  Mouse skeletal muscle

• Positive Control 5:

  Rat heart

• Positive Control 6:

  Rat liver

• NCBI Official Name:

  Interleukin 10 receptor subunit beta

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2, interleukin-10 receptor subunit beta, IL-10 receptor subunit beta, IL-10R subunit 2, IL-10R subunit beta, IL-10RB, cytokine receptor class-II CRF2-4, cytokine receptor class-II member 4, cytokine receptor family 2 member 4, cytokine receptor family II, member 4, interleukin 10 receptor, beta, interleukin-10 receptor subunit 2

• Tested Applications:

  WB

• Physical Properties:

  Liquid