RAPH1 Antibody

• Background:

  This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  65059

• Swiss Prot:

  Q70E73

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RAPH1 (NP_998754.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  SKOV3

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 200kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:200 - 1:2000

• Symbol:

  RAPH1

• Positive Control 2:

  HeLa

• Positive Control 3:

  HepG2

• Positive Control 4:

  Mouse brain

• NCBI Official Name:

  Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ALS2CR18, ALS2CR9, LPD, PREL-2, PREL2, RMO1, RalGDS/AF-6, ras-associated and pleckstrin homology domains-containing protein 1, amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 18, amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 9, lamellipodin, proline-rich EVH1 ligand 2

• Tested Applications:

  WB

• Physical Properties:

  Liquid