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PDCD10 Antibody, KO Validated

CAT: 0223-16-032Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-16-032Size:100 µL
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Background
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
NCBI Gene ID
11235
Swiss Prot
Q9BUL8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Apoptosis, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
A-431
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 26kDa
Fragment
IgG
Symbol
PDCD10
Positive Control 2
HepG2
Positive Control 3
Jurkat
Positive Control 4
MCF7
Positive Control 5
Mouse thymus
Positive Control 6
Mouse brain
NCBI Official Name
Programmed cell death protein 10
NCBI Organism
Homo sapiens
Other Product Names
Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15, PDCD10, CCM3, TFAR15
Tested Applications
WB, IF
Physical Properties
Liquid

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