PRG4 Antibody

• Background:

  The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  10216

• Swiss Prot:

  Q92954

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1264-1363 of human PRG4 (NP_001121180.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 150kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:200 - 1:2000

• Symbol:

  PRG4

• NCBI Official Name:

  Proteoglycan 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PRG4, proteoglycan 4, CACP, FLJ32635, HAPO, JCAP, MSF, SZP, bG174L6.2, Jacobs camptodactyly-arthropathy-pericarditis syndrome, articular superficial zone protein, bG174L6.2 (MSF: megakaryocyte stimulating factor), camptodactyly, arthropathy, coxa vara

• Tested Applications:

  WB

• Physical Properties:

  Liquid