KCNMA1 Antibody

• Background:

  MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

• NCBI Gene ID:

  3778

• Swiss Prot:

  Q12791

• Host:

  Rabbit

• Reactivity:

  Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 850-950 of human KCNMA1 (NP_001258447.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Innate Immunity, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Rat brain

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 137kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:200 - 1:2000

• Symbol:

  KCNMA1

• NCBI Official Name:

  Potassium large conductance calcium-activated channel, subfamily M, alpha member 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Stretch-activated Kca channel, large conductance calcium-activated potassium channel subfamily M alpha member 1, bA205K10.1 (potassium large conductance calcium-activaed channel, subfamily M, alpha member 1), OTTHUMP00000064165, OTTHUMP00000064164, OTTHUMP00000064162, OTTHUMP00000064161, OTTHUMP00000064160, OTTHUMP00000064159, OTTHUMP00000064158, OTTHUMP00000064157, OTTHUMP00000064156, OTTHUMP00000064155, OTTHUMP00000064154, OTTHUMP00000060198, Drosophila slowpoke-like, BKCA alpha subunit, mSLO1, SLO1, SLO-ALPHA, SLO, SAKCA, MaxiK, MGC71881, KCa1.1, DKFZp686K1437, BKTM, potassium large conductance calcium-activated channel, alpha member 1, KCNMA1, KCNMA

• Tested Applications:

  WB

• Physical Properties:

  Liquid