ATP1A4 Antibody

• Background:

  The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.

• NCBI Gene ID:

  480

• Swiss Prot:

  Q13733

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human ATP1A4 (NP_653300.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  Mouse testis

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 100kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:200 - 1:2000

• Symbol:

  ATP1A4

• Positive Control 2:

  Mouse brain

• Positive Control 3:

  Mouse kidney

• Positive Control 4:

  Rat testis

• Positive Control 5:

  Rat brain

• Positive Control 6:

  Rat kidney

• NCBI Official Name:

  ATPase Na+/K+ transporting subunit alpha 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ATP1A1, ATP1AL2, sodium/potassium-transporting ATPase subunit alpha-4, ATPase, Na+/K+ transporting, alpha 4 polypeptide, ATPase, Na+/K+ transporting, alpha polypeptide-like 2, Na (+) /K (+) ATPase alpha-4 subunit, Na+/K+ ATPase 4, Na+/K+ ATPase, alpha-D polypeptide, Na, K-ATPase subunit alpha-C, sodium pump 4, sodium pump subunit alpha-4, sodium-potassium ATPase catalytic subunit alpha-4, sodium/potassium-transporting ATPase alpha-4 chain

• Tested Applications:

  WB

• Physical Properties:

  Liquid