TP53BP2 Antibody

• Background:

  This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  7159

• Swiss Prot:

  Q13625

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human TP53BP2 (NP_001026855.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  DU145

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 170kDa

• Fragment:

  IgG

• Symbol:

  TP53BP2

• Positive Control 2:

  OVCAR3

• Positive Control 3:

  K562

• Positive Control 4:

  A-549

• NCBI Official Name:

  Tumor protein p53 binding protein, 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TP53BP2, BBP, 53BP2, ASPP2, P53BP2, PPP1R13A

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid