SIM2 Antibody

CAT: 0223-15-877Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-15-877Size:100 µL
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Background
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
NCBI Gene ID
6493
Swiss Prot
Q14190
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 342-525 of human SIM2 (NP_033664.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Transcription
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 56kDa
Fragment
IgG
Symbol
SIM2
Positive Control 2
HepG2
NCBI Official Name
Single-minded family bHLH transcription factor 2
NCBI Organism
Homo sapiens
Other Product Names
Single-minded homolog 2, short isoform, single-minded homolog 2, class E basic helix-loop-helix protein 15, OTTHUMP00000109044, bHLHe15, SIM, MGC119447, single-minded homolog 2 (Drosophila), SIM2, BHLHE15
Tested Applications
WB, IHC
Physical Properties
Liquid

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