DCN Antibody

• Background :

  This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.

• NCBI Gene ID :

  1634

• Swiss Prot :

  P07585

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 31-359 of human DCN (NP_598010.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  HeLa

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 45kDa

• Fragment :

  IgG

• Symbol :

  DCN

• Positive Control 2 :

  A-549

• NCBI Official Name :

  Decorin

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Small leucine-rich protein 1B, proteoglycan core protein, dermatan sulphate proteoglycans II, decorin proteoglycan, bone proteoglycan II, SLRR1B, PGS2, PGII, PG40, DSPG2, CSCD, decorin, DCN

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid