POT1 Antibody

• Background :

  This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

• NCBI Gene ID :

  25913

• Swiss Prot :

  Q9NUX5

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle

• Purification :

  Affinity purification

• Positive Control :

  A-431

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 75kDa

• Fragment :

  IgG

• Symbol :

  POT1

• Positive Control 2 :

  HeLa

• Positive Control 3 :

  DU145

• Positive Control 4 :

  Mouse liver

• NCBI Official Name :

  Protection of telomeres 1

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CMM1GLM9, HPOT1, protection of telomeres protein 1, POT1-like telomere end-binding protein, protection of telomeres 1 homolog

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid