ERLIN1 Antibody

• Background :

  The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.

• NCBI Gene ID :

  10613

• Swiss Prot :

  O75477

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 259-348 of human ERLIN1 (NP_006450.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  293T

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 39kDa

• Fragment :

  IgG

• Symbol :

  ERLIN1

• Positive Control 2 :

  HepG2

• Positive Control 3 :

  BxPC-3

• Positive Control 4 :

  DU145

• Positive Control 5 :

  OVCAR3

• Positive Control 6 :

  Mouse kidney

• NCBI Official Name :

  ER lipid raft associated 1

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  ERLIN1, C10orf69, Erlin-1, KE04, KEO4, RP11-316M21.1, SPFH1, SPG62

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid