SLC22A2 Antibody

• Background:

  Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is one of the three similar cation transporters. SLC22A2 contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  6582

• Swiss Prot:

  O15244

• Accession Number:

  NP_003049

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC22A2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC22A2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  62 kDa

• Applications Notes:

  SLC22A2 antibody can be used for detection of SLC22A2 by ELISA at 1:312500. SLC22A2 antibody can be used for detection of SLC22A2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SLC22A2

• NCBI Official Name:

  Solute carrier family 22 (organic cation transporter), member 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Pelis, R.M., Am. J. Physiol. Renal Physiol. 290 (5), F1118-F1126 (2006) .

• Other Product Names:

  SLC22A2, MGC32628, OCT2, 41914

• Tested Applications:

  ELISA, WB

• Protein ID:

  302148518

• Physical Properties:

  Liquid