SLC22A2 Antibody

CAT: 0223-29-915Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-29-915Size:100 µL
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Background
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is one of the three similar cation transporters. SLC22A2 contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6582
Swiss Prot
O15244
Accession Number
NP_003049
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC22A2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC22A2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
62 kDa
Applications Notes
SLC22A2 antibody can be used for detection of SLC22A2 by ELISA at 1:312500. SLC22A2 antibody can be used for detection of SLC22A2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SLC22A2
NCBI Official Name
Solute carrier family 22 (organic cation transporter), member 2
NCBI Organism
Homo sapiens
Background Reference 01
Pelis, R.M., Am. J. Physiol. Renal Physiol. 290 (5), F1118-F1126 (2006) .
Other Product Names
SLC22A2, MGC32628, OCT2, 41914
Tested Applications
ELISA, WB
Protein ID
302148518
Physical Properties
Liquid

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