BCAM Antibody

• Background :

  This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu (a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  4059

• Swiss Prot :

  P50895

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 352-547 of human BCAM (NP_005572.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology

• Purification :

  Affinity purification

• Positive Control :

  Mouse lung

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 90kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  BCAM

• NCBI Official Name :

  Basal cell adhesion molecule (Lutheran blood group)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  AU, CD239, LU, MSK19, basal cell adhesion molecule, Auberger b antigen, B-CAM cell surface glycoprotein, B-cell adhesion molecule, F8/G253 antigen, Lutheran blood group variant LUGA, basal cell adhesion molecule (Lu and Au blood groups)

• Tested Applications :

  WB

• Physical Properties :

  Liquid