BCAM Antibody

CAT: 0223-15-702Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-15-702Size:100 µL
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Background
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu (a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4059
Swiss Prot
P50895
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 352-547 of human BCAM (NP_005572.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
Mouse lung
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 90kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
BCAM
NCBI Official Name
Basal cell adhesion molecule (Lutheran blood group)
NCBI Organism
Homo sapiens
Other Product Names
AU, CD239, LU, MSK19, basal cell adhesion molecule, Auberger b antigen, B-CAM cell surface glycoprotein, B-cell adhesion molecule, F8/G253 antigen, Lutheran blood group variant LUGA, basal cell adhesion molecule (Lu and Au blood groups)
Tested Applications
WB
Physical Properties
Liquid

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A72890-100ULBCAM Antibody

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