EPS8 Antibody

• Background:

  This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

• NCBI Gene ID:

  2059

• Swiss Prot:

  Q12929

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human EPS8 (NP_004438.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Growth Factors, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  U-251MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 100kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  EPS8

• Positive Control 2:

  HeLa

• Positive Control 3:

  HepG2

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Rat lung

• NCBI Official Name:

  Epidermal growth factor receptor pathway substrate 8

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  EPS8, epidermal growth factor receptor pathway substrate 8

• Tested Applications:

  WB

• Physical Properties:

  Liquid