FOSB Antibody

• Background:

  The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  2354

• Swiss Prot:

  P53539

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FOSB (NP_006723.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Transcription

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 37kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  FOSB

• Positive Control 2:

  SKOV3

• Positive Control 3:

  HeLa

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Rat brain

• NCBI Official Name:

  FBJ murine osteosarcoma viral oncogene homolog B

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  FOSB, AP-1, G0S3, GOS3, GOSB

• Tested Applications:

  WB

• Physical Properties:

  Liquid