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MTRR Antibody

CAT: 0223-15-635Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-15-635Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the ferredoxin-NADP (+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants.
NCBI Gene ID
4552
Swiss Prot
Q9UBK8
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human MTRR (NP_002445.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MTRR
Positive Control 2
HeLa
Positive Control 3
LO2
Positive Control 4
293T
NCBI Official Name
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NCBI Organism
Homo sapiens
Other Product Names
MSR, cblE, methionine synthase reductase, [methionine synthase]-cobalamin methyltransferase (cob (II) alamin reducing), methionine synthase reductase, mitochondrial
Tested Applications
WB
Physical Properties
Liquid

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