MTRR Antibody

• Background:

  This gene encodes a member of the ferredoxin-NADP (+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants.

• NCBI Gene ID:

  4552

• Swiss Prot:

  Q9UBK8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human MTRR (NP_002445.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 80kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  MTRR

• Positive Control 2:

  HeLa

• Positive Control 3:

  LO2

• Positive Control 4:

  293T

• NCBI Official Name:

  5-methyltetrahydrofolate-homocysteine methyltransferase reductase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  MSR, cblE, methionine synthase reductase, [methionine synthase]-cobalamin methyltransferase (cob (II) alamin reducing), methionine synthase reductase, mitochondrial

• Tested Applications:

  WB

• Physical Properties:

  Liquid