CNKSR2 Antibody

• Background:

  This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  22866

• Swiss Prot:

  Q8WXI2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 400-750 of human CNKSR2 (NP_055742.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 117kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  CNKSR2

• Positive Control 2:

  Jurkat

• Positive Control 3:

  HepG2

• NCBI Official Name:

  Connector enhancer of kinase suppressor of Ras 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CNK2, KSR2, MAGUIN, MRXSHG, connector enhancer of kinase suppressor of ras 2, CNK homolog protein 2, connector enhancer of KSR2, membrane-associated guanylate kinase-interacting protein

• Tested Applications:

  WB

• Physical Properties:

  Liquid