PROC Antibody

• Background :

  This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

• NCBI Gene ID :

  5624

• Swiss Prot :

  P04070

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 182-461 of human PROC (NP_000303.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cell Cycle

• Purification :

  Affinity purification

• Positive Control :

  ES-2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 50kDa

• Fragment :

  IgG

• Symbol :

  PROC

• NCBI Official Name :

  Protein C (inactivator of coagulation factors Va and VIIIa)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PROC, PROC1, PC, APC, THPH3, THPH4

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid