SPDEF Antibody

• Background:

  The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  25803

• Swiss Prot:

  O95238

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human SPDEF (NP_036523.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Transcription

• Purification:

  Affinity purification

• Positive Control:

  Rat ovary

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 50kDa

• Fragment:

  IgG

• Symbol:

  SPDEF

• NCBI Official Name:

  SAM pointed domain containing ETS transcription factor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SPDEF, PDEF, RP11-375E1__A.3, bA375E1.3

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid