EDAR Antibody

• Background:

  This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

• NCBI Gene ID:

  10913

• Swiss Prot:

  Q9UNE0

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 27-187 of human EDAR (NP_071731.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Growth Factors, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse lung

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 48kDa

• Fragment:

  IgG

• Symbol:

  EDAR

• Positive Control 2:

  Mouse liver

• NCBI Official Name:

  Ectodysplasin A receptor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  EDAR, DL, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1, ECTD10A, ECTD10B

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid