APOC3 Antibody

• Background:

  Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

• NCBI Gene ID:

  345

• Swiss Prot:

  P02656

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-99 of human APOC3 (NP_000031.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 11kDa

• Fragment:

  IgG

• Symbol:

  APOC3

• Positive Control 2:

  HT-29

• Positive Control 3:

  Mouse liver

• Positive Control 4:

  Mouse small intestine

• Positive Control 5:

  Rat small intestine

• NCBI Official Name:

  Apolipoprotein C3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  APOCIII, apolipoprotein C-III

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid