APOC2 Antibody

• Background:

  APOC2 is secreted in plasma where it is a component of very low density lipoprotein. The protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in the gene encoding this protein cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.

• NCBI Gene ID:

  344

• Swiss Prot:

  P02655

• Accession Number:

  P02655

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This APOC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the Central region of human APOC2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  11 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  APOC2

• NCBI Official Name:

  Apolipoprotein C-II

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bahri, R., Lipids Health Dis 7, 46 (2008) Hegele, R.A., Dis. Markers (2), 73-80 (1991) Bengtsson-Olivecrona, G., Eur. J. Biochem. 192 (2), 515-521 (1990)

• Other Product Names:

  Apolipoprotein C-II, Apo-CII, ApoC-II, Apolipoprotein C2, Proapolipoprotein C-II, ProapoC-II, APOC2, APC2

• Tested Applications:

  WB, IHC-P

• Protein ID:

  114022

• Physical Properties:

  Liquid