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OGG1 Antibody

CAT: 0223-15-228Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-15-228Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
NCBI Gene ID
4968
Swiss Prot
O15527
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human OGG1 (NP_002533.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Affinity purification
Positive Control
Mouse heart
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 36kDa
Fragment
IgG
Symbol
OGG1
Positive Control 2
Rat heart
NCBI Official Name
N-glycosylase/DNA lyase
NCBI Organism
Homo sapiens
Other Product Names
N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, 322-, DNA- (apurinic or apyrimidinic site) lyase, AP lyase, OGG1, MMH, MUTM, OGH1
Tested Applications
WB, IHC
Physical Properties
Liquid

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