KARS Antibody

• Background :

  Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  3735

• Swiss Prot :

  Q15046

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human KARS (NP_005539.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  HepG2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 75kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  KARS

• Positive Control 2 :

  Jurkat

• Positive Control 3 :

  HeLa

• Positive Control 4 :

  293T

• Positive Control 5 :

  Mouse heart

• Positive Control 6 :

  Mouse kidney

• NCBI Official Name :

  Lysyl-tRNA synthetase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  KARS, KRS, KARS1, KARS2, CMTRIB, DFNB89

• Tested Applications :

  WB

• Physical Properties :

  Liquid