KARS Antibody

• Background:

  Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  3735

• Swiss Prot:

  Q15046

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human KARS (NP_005539.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 75kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  KARS

• Positive Control 2:

  Jurkat

• Positive Control 3:

  HeLa

• Positive Control 4:

  293T

• Positive Control 5:

  Mouse heart

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Lysyl-tRNA synthetase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  KARS, KRS, KARS1, KARS2, CMTRIB, DFNB89

• Tested Applications:

  WB

• Physical Properties:

  Liquid