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Mitofusin 2 Antibody

CAT: 0223-15-100Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-15-100Size:100 µL
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Background
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
NCBI Gene ID
170731
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 687-757 of mouse Mitofusin 2 (NP_573464.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Autophagy, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 86kDa
Fragment
IgG
Symbol
MFN2
Positive Control 2
Rat brain
NCBI Official Name
Mitofusin 2
NCBI Organism
Mus musculus
Other Product Names
D630023P19Rik, Fzo, mitofusin-2, HSG protein, hypertension related protein 1, mitochondrial assembly regulatory factor, transmembrane GTPase MFN2
Tested Applications
WB, IHC
Physical Properties
Liquid

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