TCAP Antibody

• Background:

  Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

• NCBI Gene ID:

  8557

• Swiss Prot:

  O15273

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human TCAP (NP_003664.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  Mouse heart

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 19kDa

• Fragment:

  IgG

• Symbol:

  TCAP

• Positive Control 2:

  Mouse skeletal muscle

• NCBI Official Name:

  Titin-cap

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TCAP, CMD1N, LGMD2G, T-cap, TELE, telethonin

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid