TCAP Antibody

• Background :

  Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

• NCBI Gene ID :

  8557

• Swiss Prot :

  O15273

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human TCAP (NP_003664.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  Mouse heart

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 19kDa

• Fragment :

  IgG

• Symbol :

  TCAP

• Positive Control 2 :

  Mouse skeletal muscle

• NCBI Official Name :

  Titin-cap

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  TCAP, CMD1N, LGMD2G, T-cap, TELE, telethonin

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid