DSP Antibody

• Background:

  This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  1832

• Swiss Prot:

  P15924

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 2750-2850 of human DSP (NP_004406.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 315kDa

• Fragment:

  IgG

• Symbol:

  DSP

• NCBI Official Name:

  Desmoplakin

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DSP, DPI, desmoplakin I, desmoplakin, 250kDa paraneoplastic pemphigus antigen, DP, DPII

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid