DLD Antibody

• Background:

  This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  1738

• Swiss Prot:

  P09622

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human DLD (NP_000099.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 54kDa

• Fragment:

  IgG

• Symbol:

  DLD

• Positive Control 2:

  BT-474

• Positive Control 3:

  K-562

• Positive Control 4:

  293T

• Positive Control 5:

  Mouse liver

• NCBI Official Name:

  Dihydrolipoamide dehydrogenase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DLD, DLDH, E3, GCSL, LAD, PHE3, DLDD

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid