UMPS Antibody

• Background :

  This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

• NCBI Gene ID :

  7372

• Swiss Prot :

  P11172

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human UMPS (NP_000364.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  HT-29

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 57kDa

• Fragment :

  IgG

• Symbol :

  UMPS

• Positive Control 2 :

  U-87MG

• Positive Control 3 :

  HeLa

• Positive Control 4 :

  LO2

• Positive Control 5 :

  Mouse brain

• Positive Control 6 :

  Mouse kidney

• NCBI Official Name :

  Uridine monophosphate synthetase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  UMPS, OPRT, RP11-71H17.9

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid