RAB7A Antibody

• Background:

  RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

• NCBI Gene ID:

  7879

• Swiss Prot:

  P51149

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RAB7A (NP_004628.4) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A-431

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 23kDa

• Fragment:

  IgG

• Symbol:

  RAB7A

• Positive Control 2:

  HeLa

• Positive Control 3:

  Mouse brain

• Positive Control 4:

  Rat brain

• NCBI Official Name:

  RAB7A, member RAS oncogene family

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RAB7A, CMT2B, PRO2706, RAB7, Ras-associated protein RAB7, Ras-related protein Rab-7a, PSN

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid