RAB27A Antibody

• Background :

  The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

• NCBI Gene ID :

  5873

• Swiss Prot :

  P51159

• Accession Number :

  P51159

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This RAB27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human RAB27A.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  25 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  RAB27A

• NCBI Official Name :

  Ras-related protein Rab-27A

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Ohbayashi, N., et al. Pigment Cell Melanoma Res 23 (3) :365-374 (2010)

• Background Reference 02 :

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 03 :

  Meeths, M., et al. Pediatr Blood Cancer 54 (4) :563-572 (2010)

• Background Reference 04 :

  Chattopadhyay, I., et al. Mutat. Res. 696 (2) :130-138 (2010)

• Other Product Names :

  Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27

• Tested Applications :

  WB

• Protein ID :

  116242744

• Physical Properties :

  Liquid