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RAB8A Antibody

CAT: 0223-18-822Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-18-822Size:100 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
NCBI Gene ID
4218
Swiss Prot
P61006
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic Peptide of human RAB8A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 25kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
RAB8A
NCBI Official Name
RAB8A, member RAS oncogene family
NCBI Organism
Homo sapiens
Other Product Names
RAB8A, MEL, RAB8
Tested Applications
WB
Physical Properties
Liquid

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ASA-B1602RAB8A Antibody

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