CLPS Antibody

• Background:

  The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  1208

• Swiss Prot:

  P04118

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human CLPS (NP_001823.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse pancreas

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 12kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  CLPS

• Positive Control 2:

  Rat pancreas

• NCBI Official Name:

  Colipase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Colipase, colipase, pancreatic, pancreatic colipase preproprotein

• Tested Applications:

  WB

• Physical Properties:

  Liquid