MOGS Antibody

• Background:

  This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb) . Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  7841

• Swiss Prot:

  Q13724

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human MOGS (NP_006293.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 80kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  MOGS

• Positive Control 2:

  LO2

• Positive Control 3:

  BxPC-3

• Positive Control 4:

  OVCAR-3

• Positive Control 5:

  Mouse Brain

• Positive Control 6:

  Mouse Liver

• NCBI Official Name:

  Mannosyl-oligosaccharide glucosidase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GCS1, DER7, GCS1, CDG2B, CWH41

• Tested Applications:

  WB

• Physical Properties:

  Liquid