ACKR3 Antibody

• Background:

  This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV) . Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

• NCBI Gene ID:

  57007

• Swiss Prot:

  P25106

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACKR3 (NP_064707.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Raji

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 55kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  ACKR3

• Positive Control 2:

  A-549

• Positive Control 3:

  U-87MG

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Rat brain

• NCBI Official Name:

  Atypical chemokine receptor 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ACKR3, atypical chemokine receptor 3, CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1, C-X-C chemokine receptor type 7, G protein-coupled receptor, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, chemokine (C-X-C motif) recepto

• Tested Applications:

  WB

• Physical Properties:

  Liquid