CDY2B Antibody

• Background:

  This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes.

• NCBI Gene ID:

  203611

• Swiss Prot:

  Q9Y6F7

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human CDY2B (NP_001001722.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 60kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:1000 - 1:3000

• Symbol:

  CDY2B

• Positive Control 2:

  Mouse kidney

• Positive Control 3:

  Rat kidney

• Positive Control 4:

  Rat liver

• NCBI Official Name:

  Chromodomain Y-linked 2B

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CDY, testis-specific chromodomain protein Y 2, Y chromosome chromodomain protein 2B, chromodomain protein, Y chromosome, 2 related, chromodomain protein, Y-linked, 2B, testis-specific chromodomain protein Y protein 2 related

• Tested Applications:

  WB

• Physical Properties:

  Liquid