TOPBP1 Antibody

• Background:

  This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

• NCBI Gene ID:

  11073

• Swiss Prot:

  Q92547

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TOPBP1 (NP_008958.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 171kDa

• Fragment:

  IgG

• Symbol:

  TOPBP1

• Positive Control 2:

  K-562

• NCBI Official Name:

  DNA topoisomerase II binding protein 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Dpb11, TOP2BP1, DNA topoisomerase 2-binding protein 1, DNA topoisomerase II-beta-binding protein 1, topoisomerase (DNA) II binding protein 1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid