Beta 2 Microglobulin Antibody, KO Validated

• Background:

  This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

• NCBI Gene ID:

  567

• Swiss Prot:

  P61769

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human beta 2 Microglobulin (NP_004039.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Validation:

  Antibody is Knockout validated.

• Field of Research:

  Cancer

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 12kDa

• Fragment:

  IgG

• Symbol:

  B2M

• Positive Control 2:

  COS7

• Positive Control 3:

  HeLa

• Positive Control 4:

  K-562

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse spleen

• NCBI Official Name:

  Beta-2-microglobulin

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  B2M Antibody: Beta-2-microglobulin

• Tested Applications:

  WB, IHC, IP

• Physical Properties:

  Liquid