DOT1L Antibody

• Background:

  The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.

• NCBI Gene ID:

  84444

• Swiss Prot:

  Q8TEK3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1400-1500 of human DOT1L (NP_115871.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  Mouse liver

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 170kDa

• Fragment:

  IgG

• Symbol:

  DOT1L

• Positive Control 2:

  Rat liver

• NCBI Official Name:

  DOT1 like histone lysine methyltransferase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DOT1, KMT4, histone-lysine N-methyltransferase, H3 lysine-79 specific, DOT1 like histone H3K79 methyltransferase, DOT1-like histone methyltransferase, DOT1-like protein, DOT1-like, histone H3 methyltransferase, H3-K79-HMTase, histone H3-K79 methyltransferase, histone methyltransferase DOT1L, lysine N-methyltransferase 4

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid