FXN / Frataxin Antibody

• Background:

  This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  2395

• Swiss Prot:

  Q16595

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 42-210 of human FXN / Frataxin (NP_000135.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  K-562

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 13kDa

• Fragment:

  IgG

• Symbol:

  FXN

• Positive Control 2:

  Jurkat

• Positive Control 3:

  Raji

• Positive Control 4:

  DU145

• Positive Control 5:

  Mouse kidney

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Frataxin, mitochondrial

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Frataxin, mitochondrial, Friedreich ataxia protein, Fxn, Frataxin intermediate form, i-FXN, Frataxin (56-210), m56-FXN, Frataxin (78-210), d-FXN, m78-FXN, Frataxin mature form, Frataxin (81-210), m81-FXN, FXN, FRDA, X25

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid