FTH1 Antibody

• Background:

  This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

• NCBI Gene ID:

  2495

• Swiss Prot:

  P02794

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-183 of human FTH1 (NP_002023.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  BT-474

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 20kDa

• Fragment:

  IgG

• Symbol:

  FTH1

• Positive Control 2:

  A-549

• Positive Control 3:

  PC-3

• Positive Control 4:

  DU145

• Positive Control 5:

  Mouse lung

• NCBI Official Name:

  Ferritin, heavy polypeptide 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  FTH1, FTH, FTHL6, MGC104426, PIG15, PLIF, FHC, HFE5

• Tested Applications:

  WB, IF, IP

• Physical Properties:

  Liquid