C5AR2 Antibody

• Background:

  This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  27202

• Swiss Prot:

  Q9P296

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 258-337 of human C5AR2 (NP_060955.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 36kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:1000 - 1:2000

• Symbol:

  C5AR2

• Positive Control 2:

  293T

• Positive Control 3:

  Mouse liver

• NCBI Official Name:

  Complement component 5a receptor 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GPR77, G-protein coupled receptor 77, GPF77, C5L2, G protein-coupled receptor 77

• Tested Applications:

  WB

• Physical Properties:

  Liquid