MTAP Antibody

• Background:

  This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.

• NCBI Gene ID:

  4507

• Swiss Prot:

  Q13126

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human MTAP (NP_002442.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  22Rv1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 31kDa

• Fragment:

  IgG

• Symbol:

  MTAP

• Positive Control 2:

  293T

• Positive Control 3:

  Mouse liver

• NCBI Official Name:

  Methylthioadenosine phosphorylase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus, S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAPase, MeSAdo phosphorylase, epididymis luminal protein 249, epididymis secretory sperm binding protein

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid